Lyophilized Peptide Storage and Stability: Temperatures, Shelf Life and What Degrades Peptides
Do peptides degrade during shipping at room temperature?
Most lyophilized peptides tolerate several days at ambient temperature without meaningful degradation because they contain very little water. They should be moved to cold storage on arrival.
Why should I avoid freeze–thaw cycles?
Each cycle exposes the peptide to ice-crystal formation, concentration gradients and pH shifts that promote aggregation and degradation. Freezing single-use aliquots avoids the problem.
Why let a vial warm up before opening it?
Opening a cold vial causes moisture from the air to condense on the powder. Water is the main driver of peptide degradation.
Which amino acids make a peptide less stable?
Methionine, cysteine and tryptophan are prone to oxidation; asparagine and glutamine to deamidation; aspartic acid–proline bonds to acid hydrolysis.
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Research use only. All products sold by Zen Well Labs are intended strictly for in-vitro laboratory research. They are not drugs, foods, cosmetics or dietary supplements, are not approved by the FDA for any use, and are not for human or veterinary use. Nothing on this page is medical advice.
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